
Proteonano™ Plasma Proteome Enrichment Kit
Nanoparticle enrichment of human plasma prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.
PN001-3-08 · PN001-3
Authorised partner and distributor for Nanomics Biotechnology in India. Surface-functionalised magnetic nanoparticles compress the dynamic range of plasma, serum, CSF, saliva, secretome and EV samples before LC-MS, so the proteins beneath albumin and immunoglobulin become measurable. Kits ship complete, and every kit comes in an 8-test evaluation pack.
The problem it solves
Plasma protein concentrations span more than ten orders of magnitude, and a few dozen proteins account for most of the mass. Inject neat plasma and the instrument spends its time re-measuring albumin; immunodepletion removes the known offenders but carries an unpredictable share of everything else with them.
Monodisperse magnetic nanoparticles carry short synthetic peptide ligands. Incubated with plasma they preferentially capture lower-abundance proteins, so the most abundant are relatively depleted. After a magnetic wash, what is digested has a far flatter abundance distribution.
At the Lorne Proteomics Symposium (Feb 2026) Nanomics reported more than 5,000 protein groups from 10 µL plasma with CVs below 15% on an Evosep One-Orbitrap Astral system, at up to 500 samples per day automated. Depth on other platforms will differ; the 8-test evaluation pack exists so that a pilot can be run on your own instrument before a cohort is committed.
Nanomics Biotech named omicslink its authorised distributor for India, supporting local product communication, quotation, ordering and workflow discussions. Read the announcement.
Source: Wu H., poster 149, 31st Lorne Proteomics Symposium, 7 Feb 2026 (abstract). Kit composition per manufacturer documentation; product images courtesy of Nanomics Biotechnology.
Enrichment kits · by sample type

Nanoparticle enrichment of human plasma prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.
PN001-3-08 · PN001-3

Nanoparticle enrichment of human serum prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.
PN-SERA-08 · PN-SERA-48

Nanoparticle enrichment of cerebrospinal fluid prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.
CSFK001-08 · CSFK001

Nanoparticle enrichment of saliva prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.
SLVK001-08 · SLVK001

Nanoparticle enrichment of cell secretome prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.
SCTK001-08 · SCTK001

Nanoparticle enrichment of extracellular vesicles prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.
EXSK001-08 · EXSK001

Nanoparticle enrichment of mouse plasma prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.
MUSK001-08 · MUSK001

Protein aggregation capture on magnetic beads for cells and tissue: lysate to clean peptides in one bead-based, plate-compatible workflow, with digestion reagents and desalting included.
SP3K003 · SP3K001
Phosphoproteome enrichment
Phosphoproteomics is a core service in our own laboratory, see how we run it.

Phosphopeptide enrichment and clean-up for phosphoproteomics; the same chemistry sits in our own phosphoproteomics workflow.
PHSK-A-24 · PHSK-A-96

Phosphopeptide enrichment and clean-up for phosphoproteomics; the same chemistry sits in our own phosphoproteomics workflow.
PHSK-B-24 · PHSK-B-96

96-test peptide clean-up used across the Proteonano™ range.
PEC-A-96
Automation

Automates the Proteonano™ enrichment workflow end to end for cohort-scale plasma and biofluid studies. A capital purchase arranged with Nanomics after a demonstration.
Request a demonstration
Higher-throughput configuration for core facilities and clinical cohorts. Low-binding filter tips, deep-well plates, reservoirs and adapters for both workstations are quoted alongside your kits.
Ask about consumablesFor research use only. Not for use in diagnostic procedures.
Applications
Compress the dynamic range of plasma so that mid- and low-abundance proteins are quantified across hundreds of samples.
Depletion vs enrichment 02Low-volume cerebrospinal fluid enriched for the proteins that reflect brain and neuro-inflammatory biology.
Biomarker discovery 03EV-associated proteomes from plasma, culture medium and other fluids for liquid-biopsy and signalling studies.
Discuss an EV study 04Capture secreted proteins from cell culture without the serum-protein background dominating the run.
Cell-based proteomics 05A dedicated mouse plasma kit for pharmacology and disease-model cohorts where volumes are small.
Preclinical proteomics 06TiO₂ and magnetic-bead phosphopeptide enrichment with a matched clean-up, for signalling studies from cells and tissue.
Phospho guideEvery kit comes in an 8-test evaluation size with protocol support. If you would like to see the chemistry on your own cohort before deciding, our proteomics team can discuss pilot options.