Nanomics · Proteome enrichment

Proteonano™ nanoparticle enrichment,for deep plasma and biofluid proteomics.

Authorised partner and distributor for Nanomics Biotechnology in India. Surface-functionalised magnetic nanoparticles compress the dynamic range of plasma, serum, CSF, saliva, secretome and EV samples before LC-MS, so the proteins beneath albumin and immunoglobulin become measurable. Kits ship complete, and every kit comes in an 8-test evaluation pack.

The problem it solves

Plasma hides almost everything worth measuring.

Plasma protein concentrations span more than ten orders of magnitude, and a few dozen proteins account for most of the mass. Inject neat plasma and the instrument spends its time re-measuring albumin; immunodepletion removes the known offenders but carries an unpredictable share of everything else with them.

Mechanism

Preferential capture of the low-abundance fraction

Monodisperse magnetic nanoparticles carry short synthetic peptide ligands. Incubated with plasma they preferentially capture lower-abundance proteins, so the most abundant are relatively depleted. After a magnetic wash, what is digested has a far flatter abundance distribution.

Manufacturer data

>5,000 protein groups from 10 µL

At the Lorne Proteomics Symposium (Feb 2026) Nanomics reported more than 5,000 protein groups from 10 µL plasma with CVs below 15% on an Evosep One-Orbitrap Astral system, at up to 500 samples per day automated. Depth on other platforms will differ; the 8-test evaluation pack exists so that a pilot can be run on your own instrument before a cohort is committed.

Partnership

Announced by Nanomics, July 2026

Nanomics Biotech named omicslink its authorised distributor for India, supporting local product communication, quotation, ordering and workflow discussions. Read the announcement.

Source: Wu H., poster 149, 31st Lorne Proteomics Symposium, 7 Feb 2026 (abstract). Kit composition per manufacturer documentation; product images courtesy of Nanomics Biotechnology.

Enrichment kits · by sample type

Start with what isin your freezer.

Proteonano™ Plasma Proteome Enrichment Kit
Enrichment kit · Human plasma

Proteonano™ Plasma Proteome Enrichment Kit

Nanoparticle enrichment of human plasma prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.

PN001-3-08 · PN001-3

Proteonano™ Serum Proteome Enrichment Kit
Enrichment kit · Human serum

Proteonano™ Serum Proteome Enrichment Kit

Nanoparticle enrichment of human serum prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.

PN-SERA-08 · PN-SERA-48

Proteonano™ CSF Proteome Enrichment Kit
Enrichment kit · Cerebrospinal fluid

Proteonano™ CSF Proteome Enrichment Kit

Nanoparticle enrichment of cerebrospinal fluid prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.

CSFK001-08 · CSFK001

Proteonano™ Saliva Proteome Enrichment Kit
Enrichment kit · Saliva

Proteonano™ Saliva Proteome Enrichment Kit

Nanoparticle enrichment of saliva prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.

SLVK001-08 · SLVK001

Proteonano™ Cell Secretome Proteome Enrichment Kit
Enrichment kit · Cell secretome

Proteonano™ Cell Secretome Proteome Enrichment Kit

Nanoparticle enrichment of cell secretome prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.

SCTK001-08 · SCTK001

Proteonano™ EV Proteome Enrichment Kit
Enrichment kit · Extracellular vesicles

Proteonano™ EV Proteome Enrichment Kit

Nanoparticle enrichment of extracellular vesicles prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.

EXSK001-08 · EXSK001

Proteonano™ Mouse Plasma Proteome Enrichment Kit
Enrichment kit · Mouse plasma

Proteonano™ Mouse Plasma Proteome Enrichment Kit

Nanoparticle enrichment of mouse plasma prior to LC-MS. Kit contains enrichment nanoparticles, pre-treatment reagent, enzyme and C18 desalting. The 8-test pack is an evaluation size.

MUSK001-08 · MUSK001

Proteonano™ PAC Proteome Extraction Kit
Extraction kit · Cells & tissue

Proteonano™ PAC Proteome Extraction Kit

Protein aggregation capture on magnetic beads for cells and tissue: lysate to clean peptides in one bead-based, plate-compatible workflow, with digestion reagents and desalting included.

SP3K003 · SP3K001

Phosphoproteome enrichment

Two chemistries, one clean-up.

Phosphoproteomics is a core service in our own laboratory, see how we run it.

Proteonano™ TiO₂ Phosphoproteome Enrichment Kit
Phospho enrichment

Proteonano™ TiO₂ Phosphoproteome Enrichment Kit

Phosphopeptide enrichment and clean-up for phosphoproteomics; the same chemistry sits in our own phosphoproteomics workflow.

PHSK-A-24 · PHSK-A-96

Proteonano™ Magbeads Phosphoproteome Enrichment Kit
Phospho enrichment

Proteonano™ Magbeads Phosphoproteome Enrichment Kit

Phosphopeptide enrichment and clean-up for phosphoproteomics; the same chemistry sits in our own phosphoproteomics workflow.

PHSK-B-24 · PHSK-B-96

Proteonano™ P-Clean Peptide Clean-up Kit
Phospho enrichment

Proteonano™ P-Clean Peptide Clean-up Kit

96-test peptide clean-up used across the Proteonano™ range.

PEC-A-96

Automation

Nanomation™ G1 workstations and consumables.

Nanomation G1 Basic workstation

Nanomation™ G1 Basic

Automates the Proteonano™ enrichment workflow end to end for cohort-scale plasma and biofluid studies. A capital purchase arranged with Nanomics after a demonstration.

Request a demonstration
Nanomation G1 Pro workstation

Nanomation™ G1 Pro

Higher-throughput configuration for core facilities and clinical cohorts. Low-binding filter tips, deep-well plates, reservoirs and adapters for both workstations are quoted alongside your kits.

Ask about consumables

For research use only. Not for use in diagnostic procedures.

Get started

Start with an evaluation pack, or with a conversation.

Every kit comes in an 8-test evaluation size with protocol support. If you would like to see the chemistry on your own cohort before deciding, our proteomics team can discuss pilot options.